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About Parkinson’s Disease1,2

Parkinson’s is a chronic and progressive disorder of the central nervous system. It affects how your body moves and
can also affect the way you think.

Parkinson’s belongs to a group of disorders known as movement disorders.

Chronic means it is a long-term condition—once you have it, you will always have it.

Progressive means your symptoms will evolve over time.

A movement disorder is a neurological condition. It affects the speed and ease of your movement.

Learn more about Parkinson's disease from a healthcare professional.
Then, click here to see how RYTARY has helped real people with PD cope with their symptoms.


Your brain might tell your body to move a certain way, but that message doesn’t get through properly and your body stops,
freezes, or moves another way instead. Think of it like a bad phone connection where you can only hear every other word.
Or like reading an instruction manual, but every other word is missing so you can’t understand the directions.

Why is dopamine important, and what happens when it decreases?1-3

Everyone has a chemical in his or her body called dopamine.

Dopamine sends messages that control our movement and coordination. As we age, we produce less dopamine, and our dopamine-producing cells in the brain start to die off.

When dopamine-producing cells in the brain die off rapidly, it becomes difficult for our brains to tell our bodies what to do. You notice this when it’s time to move your body and perform daily activities such as getting up out of a chair, walking, brushing your hair, or eating a meal.

This is what happens when you have Parkinson’s disease. People with Parkinson’s have low levels of dopamine in their body. This makes it a challenge for the brain to send signals to the body regarding movement. Yet, there are treatments that may help.4,5


No one knows exactly what causes Parkinson’s disease. However, experts think that the disease is caused by a combination of factors.6

Risk factors

  • Age
  • Heredity
  • Gender
  • Environmental
    • Rural living
    • Exposure to pesticides or herbicides
    • Well-water drinking
    • Working with solvents

How many people
are affected by Parkinson’s disease?

Parkinson’s Disease by the Numbers

1 million people in the United States have Parkinson’s disease.7
Each day, about
164 people receive
a diagnosis of Parkinson’s disease.7
More people develop Parkinson’s disease than multiple sclerosis, muscular dystrophy, and Lou Gehrig’s disease combined.8-11

Steps You Can Take

Learn About Parkinson’s Disease
Learn as much as you can
about your condition.
Understand the Side Effects and Benefits of the Medication
Understand the benefits and side
effects of the medication you will take.
Make Helpful Lifestyle Changes
Learn how to make helpful
lifestyle changes.
Create a Support System
Create a support system.
Stay Positive
Stay positive.
Take Complete Notes When Visiting the Doctor
Take complete notes when
you visit your doctor.

Every Moment Counts.
Ask your doctor today if RYTARY is right for you.


RYTARY is a prescription medication that contains a combination of carbidopa and levodopa for the treatment of Parkinson’s disease, Parkinson’s disease caused by infection or inflammation of the brain, or Parkinson’s disease like symptoms that may result from carbon monoxide or manganese poisoning.


Do not take RYTARY with antidepressant medications known as nonselective monoamine oxidase (MAO) inhibitors because taking these two drugs within two weeks of each other can result in high blood pressure.

Taking RYTARY may result in falling asleep while engaged in normal activities, even without warning and as late as one year after starting to take RYTARY. Other sedating medicines and alcohol taken together with RYTARY may have additional sedative effects. Tell your healthcare provider if you have any kind of sleep disorder or are experiencing drowsiness or sleepiness.

Some side effects of taking RYTARY including sleepiness and dizziness may affect your ability to drive or operate machinery. Do not drive a car, operate a machine, or do anything that requires you to be alert until you know how RYTARY affects you.

Talk to your healthcare provider before you lower the dose or stop taking RYTARY, as this may result in serious side effects. Call your healthcare provider immediately if you develop withdrawal symptoms such as fever, confusion, or severe muscle stiffness.

Make sure to tell your healthcare provider if you have any heart conditions, especially if you have had a heart attack and also have irregular heartbeats. Some people with a history of or risk factors for heart disease have experienced heart problems while taking RYTARY.

Some patients taking RYTARY can experience hallucinations (unreal visions, sounds, or sensations) or abnormal thoughts and behaviors (such as excessive suspicion, believing things that are not real, confusion, agitation, aggressive behavior, and disorganized thinking). If you have hallucinations or abnormal thoughts or behaviors, talk with your healthcare provider.

Some patients taking certain medicines to treat Parkinson’s disease have intense urges to gamble, increased sexual urges, other intense urges, and the inability to control those urges. If you or your family members notice that you are developing unusual urges or behaviors, talk to your healthcare provider.

Tell your healthcare provider if abnormal involuntary movements appear or get worse during treatment with RYTARY.

Tell your healthcare provider if you have ever had a peptic ulcer, because RYTARY may increase your chances of having bleeding in your stomach.

Tell your healthcare provider if you have glaucoma, because RYTARY may increase the pressure in your eyes.

Parkinson’s disease patients are at an increased risk of developing melanoma, a form of skin cancer. See your healthcare provider for regular skin examinations when taking RYTARY.

The most common side effects that may occur with RYTARY include nausea, dizziness, headache, sleeplessness, abnormal dreams, dry mouth, abnormal involuntary movements, anxiety, constipation, vomiting, and low blood pressure upon rising. Rise slowly after sitting or lying down for a prolonged period.

Following use in the marketplace, some patients taking RYTARY have experienced suicidal thoughts or have attempted suicide. A causal relationship has not been established. Tell your healthcare provider if you have thoughts of suicide or have attempted suicide.

Notify your healthcare provider if you become pregnant or intend to become pregnant during therapy or if you intend to breast-feed or are breast-feeding an infant.

Adverse events following unintentional overdose with this medication have been reported. If you accidentally take more than your prescribed dose, talk to your healthcare provider right away.

Make sure you tell your healthcare provider about all of the prescription and non-prescription medications you take, including supplements, and especially those for Parkinson’s disease, heart disease, blood pressure, abnormal thoughts, tuberculosis, and sleep problems, and supplements containing iron. Do not take other carbidopa levodopa preparations with RYTARY without consulting your healthcare provider.

Be sure to take your medicine as instructed. You may take RYTARY with or without food; however, taking RYTARY with food may decrease or delay its effect. For this reason, consider taking the first dose of the day about 1 to 2 hours before eating. Swallow RYTARY whole; do not chew, divide, or crush. If you have difficulty swallowing the capsule, twist apart both halves and sprinkle the entire contents of both halves of the capsule on a small amount of applesauce (1 to 2 tablespoons). Consume the mixture immediately. Do not store the drug/food mixture for future use.

Note: The above information for patients being treated with RYTARY is intended to aid in the safe and effective use of this medication. It is not a disclosure of all possible adverse or intended effects. Tell your healthcare provider if you have any side effects while taking RYTARY. He or she can make adjustments that may reduce these effects.

To report SUSPECTED ADVERSE REACTIONS, contact Amneal Specialty, a division of Amneal Pharmaceuticals LLC at 1-877-835-5472 or the FDA at 1-800-FDA-1088 or

Please read the full Prescribing Information. For more information, talk to your healthcare provider.


1. Movement disorders. United States Library of Medicine, MedlinePlus website. Accessed January 25, 2017.
2. NINDS Parkinson’s Disease Information Page. National Institutes of Health, National Institute of Neurological Disorders and Stroke website. Accessed January 25, 2017.
3. Medical Management of Parkinson’s disease. Pharmacy and Therapeutics Journal. Accessed February 8, 2017.
4. Chasing the cure. Parkinson’s Disease Foundation website. Accessed February 8, 2017.
5. What Is Parkinson’s Disease? What Causes Parkinson’s Disease? Medical News Today website. Accessed
January 25, 2017.
6. What causes Parkinson's? Parkinson's Disease Foundation website. Accessed January 25, 2017.
7. Parkinson’s disease overview. National Parkinson Foundation website. Accessed January 25, 2017.
8. Statistics on Parkinson’s. Parkinson’s Disease Foundation website. Accessed January 25, 2017.
9. Multiple sclerosis by the numbers: facts, statistics, and you. Healthline. Accessed
January 25, 2017.
10. How many people are affected with muscular dystrophy (MD)? Sharecare.
muscular-dystrophy. Accessed January 25, 2017.
11. Facts you should know. ALS Association website. Accessed January 25, 2017.