INDICATION
RYTARY (carbidopa and levodopa) extended-release capsules is a prescription medication that contains a
combination of carbidopa and levodopa for the treatment of Parkinson’s disease, Parkinson’s disease caused by
infection or inflammation of the brain,
or Parkinson’s disease like symptoms that may result from carbon monoxide or manganese poisoning.
IMPORTANT SAFETY INFORMATION
Do not take RYTARY with antidepressant medications known as nonselective monoamine oxidase (MAO) inhibitors
because taking these two drugs within two weeks of each other can result in high blood pressure.
Taking RYTARY may result in falling asleep while engaged in normal activities, even without warning and as
late as one year after starting RYTARY. This may affect your ability to drive or operate machinery. Do not do
anything that
requires alertness until you know how RYTARY affects you.
Tell your healthcare provider if you have any heart conditions, especially if you have had a heart attack or
irregular heartbeats; if you experience hallucinations or abnormal thoughts and behaviors (such as excessive
suspicion, believing
things that are not real, confusion, agitation, aggressive behavior, and disorganized thinking), if you have
intense urges to gamble, increased sexual urges, other intense urges, and the inability to control those
urges; if abnormal
involuntary movements appear or get worse during treatment with RYTARY; or if you have ever had a peptic ulcer
or glaucoma.
The most common side effects that may occur with RYTARY include nausea, dizziness, headache, sleeplessness,
abnormal dreams, dry mouth, abnormal involuntary movements, anxiety, constipation, vomiting, and low blood
pressure upon rising.
Some patients taking RYTARY have experienced suicidal thoughts or have attempted suicide. Tell your
healthcare provider if you have thoughts of suicide or have attempted suicide.
Notify your healthcare provider if you become pregnant or intend to become pregnant during therapy or if you
intend to breast-feed or are breast-feeding an infant.
Talk to your healthcare provider before you lower the dose or stop taking RYTARY, as this may result in
serious side effects. Call your healthcare provider immediately if you develop withdrawal symptoms such as
fever, confusion, or
severe muscle stiffness.
Take RYTARY as instructed. You may take RYTARY with or without food; however, taking RYTARY with food may
decrease or delay its effect. For this reason, consider taking the first dose of the day about 1 to 2 hours
before eating. Swallow
RYTARY whole; do not chew, divide, or crush. If you have difficulty swallowing the capsule, twist apart both
halves and sprinkle the entire contents of both halves of the capsule on a small amount of applesauce (1 to 2
tablespoons).
Consume the mixture immediately. Do not store the drug/food mixture for future use.
Note: This information is intended to aid in the safe and effective use of RYTARY. It is not a disclosure of
all possible adverse or intended effects. Tell your healthcare provider if you have any side effects while
taking RYTARY.
He or she can make adjustments that may reduce these effects.
To report SUSPECTED ADVERSE REACTIONS, contact Amneal Specialty, a division of Amneal
Pharmaceuticals LLC at 1-877-835-5472
1-877-835-5472 or the FDA at 1-800-FDA-1088 or
www.fda.gov/medwatch.
Please read the full
Prescribing Information. For more information talk to your healthcare provider.
The individuals appearing in this piece were sponsored by Amneal Pharmaceuticals. Your experience and
results may vary.
INDICATION
RYTARY (carbidopa and levodopa) extended-release capsules is a prescription medication that contains a
combination of carbidopa and levodopa for the treatment of Parkinson’s disease, Parkinson’s disease caused by
infection or inflammation of the brain,
or Parkinson’s disease like symptoms that may result from carbon monoxide or manganese poisoning.
