RYTARY contains the same medication as IR CD/LD, but it’s formulated differently

RYTARY can fill in the valleys and smooth out the peaks created by IR CD/LD
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RYTARY was given every 6 hours, while IR CD/LD was given every 3 hours.
* Percentage deviation from levodopa average concentration at steady state.
Adapted from Hsu et al, 2015.
Predicted steady-state profile based on RYTARY dosed every 6 hours and IR CD/LD dosed every 3 hours.
The multi-dose curves of levodopa plasma concentration levels were developed based on superposition of observed data from healthy volunteers receiving single doses.

CD/LD medications are a mainstay of Parkinson’s treatment, with IR CD/LD being among the most commonly prescribed. However, the fact that it’s immediate release means that, while it works quickly, each dose lasts for shorter periods of time as Parkinson’s progresses. So once people have been taking it for a while, they begin to fluctuate between “on” and “off” periods.

RYTARY delivers each dose of medication quickly, and then sustains LD levels over a longer period of time, leaving you with less “off” time and more “on” time throughout the day.

RYTARY provides a steadier, more sustained delivery of medication vs other CD/LD treatments

RYTARY keeps LD levels steadier for longer than other CD/LD medications

RYTARY is uniquely formulated to be both immediate and extended release

Each RYTARY capsule contains a unique combination of time-release beads
  • 1/3 are immediate release, which allows
    RYTARY to start working quickly
  • 2/3 are extended release, which, when combined with the other beads, allows RYTARY to work up to 4 to 5 hours

Together, this may reduce the amount of “off” time you experience each day.

Were you taking a CD/LD
medication before RYTARY?
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